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pentobarbital will lessen the level or outcome of tacrolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will reduce the level or result of conivaptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will reduce the extent or outcome of pitolisant by affectin